On Sample Size and Power Calculation for Variant Set-Based Association Tests

Sample Size and Statistical Power Calculation in Genetic Association Studies

A sample size with sufficient statistical power is critical to the success of genetic association studies to detect causal genes of human complex diseases. Genome-wide association studies require much larger sample sizes to achieve an adequate statistical power. We estimated the statistical power with increasing numbers of markers analyzed and compared the sample sizes that were required in cas...

application of upfc based on svpwm for power quality improvement

در سالهای اخیر،اختلالات کیفیت توان مهمترین موضوع می باشد که محققان زیادی را برای پیدا کردن راه حلی برای حل آن علاقه مند ساخته است.امروزه کیفیت توان در سیستم قدرت برای مراکز صنعتی،تجاری وکاربردهای بیمارستانی مسئله مهمی می باشد.مشکل ولتاژمثل شرایط افت ولتاژواضافه جریان ناشی از اتصال کوتاه مدار یا وقوع خطا در سیستم بیشتر مورد توجه می باشد. برای مطالعه افت ولتاژ واضافه جریان،محققان زیادی کار کرده ...

Power and sample size calculations for designing rare variant sequenc - ing association studies

Recently, Wu et al. [4] have proposed the sequence kernel machine test (SKAT) to test association between genetic variants in a gene or region and a continuous or binary trait. SKAT, which uses the kernel machine regression framework, is very flexible and computationally efficient. From extensive simulation studies and real data application, it has been shown that SKAT is more powerful than the...

Sample Size Calculation and Power Analysis of Time-Averaged Difference

Tests for an upper percentile of a lognormal distribution based on samples with multiple detection limits and sample-size calculation.

The problem of determining sample size for testing an upper percentile of a lognormal distribution based on samples with multiple detection limits is considered. Two tests, the signed likelihood ratio test and another test based on a pivotal statistic, are outlined. These tests are very satisfactory in controlling type I error rates and comparable in terms of powers. Procedures and R codes for ...